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— Can you come to my birthday party on Sunday, Mike?

— Sorry, I ______. I have to look after my little sister.

A. can B. can’t C. may D. mustn’t

B 【解析】句意：——邁克，你能在星期天來參加我的生日聚會嗎？——對不起，我不能。我必須照顧我的小妹妹。can可以，表示允許，can’t不能，不可以，表示不允許；may可以，表示允許，mustn’t禁止。Can you……?“你能/可以……嗎？”根據Sorry可知此處用否定回答，故為can’t，故選B。
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