_____the beginning of the 19th century did scientists know that all matter is made up of atoms.
A,At     B,By     C,Up to     D,Not until

D

解析試題分析:句子用了部分倒裝,所以前面用Not until
考點:倒裝的考查
點評:句首狀語為否定詞或半否定詞的句子。這類詞或短語主要有never, neither, nor, little, seldom(很少,不常), rarely(很少,罕有), hardly, scarcely(幾乎不,簡直沒有), no sooner(立即), not only, in no way(決不), at no time, few, not, no等, 用部分倒裝。部分倒裝是把be動詞、情態(tài)動詞、助動詞放到主語之前。如果句子中沒有這些詞,要在主語之前加助動詞do / does / did等,而把原來的謂語動詞變成原形放在主語之后。

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