_______ what his parents think, he is leaving home for a new job in a big city.
A．Regardless ofB．Instead ofC．In terms ofD．Lack of
A
考查短語辨析。Regardless of 不顧，不管，Instead of 代替，In terms of 就什么而言，Lack of 缺乏，句意：不顧他的父母想什么，他將離開家在大城市去找新的工作。所以選A。
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