When it ______ research into heart disease and its effects on the body, we do not have adequate substitutes for the use of animals.
A．refers toB．related toC．comes to D．talks to
C
考查句型：when it comes to 當(dāng)談到什么的時(shí)候，當(dāng)談到研究心臟病以及心臟病對(duì)人體影響的時(shí)候，我們沒(méi)有足夠的替代品在動(dòng)物身上使用。故選C。
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