I have always been honest and straightforward, and it doesn’t matter ______ I’m talking to.
A．who is it thatB．who it is that
C．it is who thatD．it is whom that
B 
考察強(qiáng)調(diào)句型的特殊疑問句。強(qiáng)調(diào)句型：it is/was 被強(qiáng)調(diào)成分that/whho其他成分。其特殊疑問句為：特殊疑問詞+一般疑問句。本題中的It是形式主語，真正的主語是橫線上的從句，使用陳述語序。故B正確。
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