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His friends ignored his advice, ______ they knew it to be helpful.
A．as ifB．sinceC．even ifD．so that
C

試題分析：考查連詞辨析。A似乎；B自從，既然；C即使；D以至于；句意：他的朋友不理睬他的建議。即使他們知道這些建議很有幫助。故C正確。
點評：連詞的辨析要根據上下文的語境和語義進行。要注意同一個連詞的不同含義的區(qū)別。
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