____there are many differences in personality, they have a lot____ common.
A．While; inB．Although; onC．In spite of; inD．Thanks to; on
A
本題易誤選C。in spite of 為介詞短語，后接名詞、代詞或短語，不能接句子，而本句第一個空后是句子形式，需填連詞， while用作連詞，其中一層意思為“雖然；盡管”; have…in common為固定短語，意思為“有共同之處”。
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