No one has yet succeeded in explaining the ___ of how life began.
A．causeB．problemC．reasonD．puzzle
A
詞義辨析。Cause原因；目標(biāo)； problem 問題，難題；reason 原因，理由，動機； puzzle 難題，迷惑。句意：還沒有人在解釋生命是如何起源的這個原因上取得成功。 reason著重指解釋或說明某事發(fā)生的理由或原因；cause著重指產(chǎn)生或造成某事發(fā)生的原因。結(jié)合語境可知選A，為最佳答案。
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