_________ you may have, you should gather your courage to face the challenge.

A．Whatever serious a problem B．However serious a problem
C．However a serious problem D．No matter how a serious problem

B

解析試題分析：考查讓步狀語從句：句意：無論你可能遇到多么嚴(yán)重的問題，你都要鼓足勇氣面對(duì)挑戰(zhàn)。Whatever后面接名詞，排除A。however/no matter how后面可以接adj+冠詞+名詞，CD都是錯(cuò)的，選B。
考點(diǎn)：考查讓步狀語從句

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