We had tried everything to improve their living conditions,but it made little .

A.good B.use

C.result D.difference

D

【解析】

試題分析：固定搭配make a difference起作用，有影響；make little difference不起作用，沒有影響；句意：我們嘗試了所有事情來提高生活條件，但是都沒有起作用。根據(jù)句意說明D正確。

考點：考查固定搭配

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