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The old lady had a son and two daughters，________treated her well，which made her very sad.
A．no one of whomB．none of whom
C．neither of themD．none of them
B
none既可指人也可指物，常暗示一定范圍，因此通常與表范圍的of短語連用；而no one(=nobody)只能指人，不能與of短語連用，neither表示兩個都不，them不能做引導詞，故選B。
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