【題目】 Experts hope an experimental drug can be as effective against the novel coronavirus in people as it has been on cells in a controlled lab environment.

The US drug, remdesivir (瑞德西韋), began clinical trials（臨床試驗(yàn)）on patients in Wuhan, Hubei province on Thursday. Other medications, including chloroquine, arbidol and darunavir have also recently been found capable of arresting viral growth in lab cells, but like remdesivir, they require more clinical trials to confirm their safety and potency on humans.

The Phase III trials for remdesivir have been approved by China’s National Medical Products Administration and is conducted by the China-Japan Friendship Hospital in Beijing and the Chinese Academy of Medical Sciences on patients at the Wuhan Jinyintan Hospital.

“A total of 761 patients will participate in two trials-one trial to assess the drugs' potency on 308 cases with mild or moderate infection, and the other on 453 severely infected patients”, Cao Bin, head of the clinical trial and vice-president of the friendship hospital, said on Wednesday.

Cao said studies have shown remdesivir is effective in inhibiting the growth of the novel coronavirus in vitro(在生物體外), meaning the procedure was done on cells in a controlled environment outside of a living organism, typically in a petri dish or test tube.

But the drug has yet to show convincing clinical evidence that it can translate its positive in vitro results into actual human patients. So, it will require strict clinical testing, Cao said.

A 35-year-old patient from the United States infected with the virus was reported seeing noticeable improvement with no obvious side effects after taking the drug, according to the New England Journal of Medicine.

Gilead Sciences, the maker of remdesivir, said in a recent statement that it has been working with government agencies on the novel coronavirus response efforts.

However, the company stressed that remdesivir is an experimental medicine that has only been used in a handful of patients, “so we do not have an appropriately full understanding of the effect of this drug ”.

【1】Why does the US drug, remdesivir, began clinical trials?

A.To replace the traditional medicine.

B.To confirm their safety and potency on humans.

C.To show whether remdesivir is effective in inhibiting the growth of the novel coronavirus in vitro.

D.To see how it takes effect.

【2】What is true according to the passage?

A.After taking the drug, a 35-year-old patient was infected with the virus.

B.Doctors had seen noticeable success treating a 35-year-old patient infected with the virus.

C.Remdesivir can cure those who are infected with the novel coronavirus.

D.Chinese Hospital does The Phase III trials independently.

【3】What’s the author's attitude towards the clinical trial of remdesivir?

A.Negative.B.Critical.C.Positive.D.Gloomy.

【4】Where is this text most likely from?

A.A diary.B.A guidebook.C.A novel.D.A magazine.

【答案】

【1】B

【2】B

【3】C

【4】D

【解析】

本文講述了針對(duì)新冠肺炎，瑞德西韋等幾種藥物進(jìn)入臨床試驗(yàn)。

【1】細(xì)節(jié)理解題。根據(jù)“they require more clinical trials to confirm their safety and potency on humans”可知，瑞德西韋這種藥開始臨床試驗(yàn)，是為了確定藥物的安全性和有效性。故選B。

【2】細(xì)節(jié)理解題。After taking the drug, a 35-year-old patient was infected with the virus. 一個(gè)35歲的病人在服用了這種藥物后，感染了這種病毒。根據(jù)“A 35-year-old patient from the United States infected with the virus was reported seeing noticeable improvement with no obvious side effects after taking the drug.”可知，一名35歲的美國(guó)病人服用該藥后，病情有明顯改善，無明顯副作用，而不是服用藥物后感染了病毒，所以A項(xiàng)表述錯(cuò)誤。Doctors had seen noticeable success treating a 35-year-old patient infected with the virus.醫(yī)生們?cè)谥斡晃?/span>35歲的病人時(shí)取得顯著成功。根據(jù)“A 35-year-old patient from the United States infected with the virus was reported seeing noticeable improvement with no obvious side effects after taking the drug.”可知，一名35歲的美國(guó)病人服用該藥后，病情有明顯改善，無明顯副作用。這名美國(guó)病人在服用瑞德西韋之后，療效顯著。所以B項(xiàng)表述正確。Remdesivir can cure those who are infected with the novel coronavirus.瑞德西韋可以治愈那些被新型冠狀病毒感染的人。根據(jù)“the company stressed that remdesivir is an experimental medicine that has only been used in a handful of patients”可知，瑞德西韋是一種實(shí)驗(yàn)性藥物，只在少數(shù)病人中使用過，并不能證明這種藥可以治愈新冠肺炎感染的病人，所以C項(xiàng)表述錯(cuò)誤。Chinese Hospital does The Phase III trials independently.中國(guó)醫(yī)院獨(dú)立進(jìn)行三期臨床試驗(yàn)。根據(jù)“The Phase III trials for remdesivir have been approved by China’s National Medical Products Administration and is conducted by the China-Japan Friendship Hospital in Beijing and the Chinese Academy of Medical Sciences on patients at the Wuhan Jinyintan Hospital.”可知，瑞德西韋的三期臨床試驗(yàn)已獲得中國(guó)國(guó)家醫(yī)療產(chǎn)品管理局的批準(zhǔn)，由北京中日友好醫(yī)院和中國(guó)醫(yī)學(xué)科學(xué)院對(duì)武漢金銀潭醫(yī)院的患者進(jìn)行，所以三期臨床試驗(yàn)是中國(guó)醫(yī)院獨(dú)立進(jìn)行，但是瑞德西韋是來自于美國(guó)的藥物，同時(shí)在美國(guó)也進(jìn)行了三期臨床試驗(yàn)。所以D項(xiàng)表述錯(cuò)誤。故選B。

【3】觀點(diǎn)態(tài)度題。根據(jù)“sExperts hope an experimental drug can be as effective against the novel coronavirus in people as it has been on cells in a controlled lab environment.”可知，由于瑞德西韋藥物在實(shí)驗(yàn)室環(huán)境中取得良好的效果，因此現(xiàn)在投入臨床試驗(yàn)，希望能獲得一樣好的效果。所以此處作者的態(tài)度是“積極的”。故選C。

【4】推理判斷題。根據(jù)“The US drug, remdesivir (瑞德西韋), began clinical trials（臨床試驗(yàn)）on patients in Wuhan, Hubei province on Thursday.”并結(jié)合全文可知，文中主要是講瑞德西韋等幾種藥物進(jìn)入臨床試驗(yàn)，所以文章最有可能來源于醫(yī)學(xué)雜志。故選D。

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